In a bold new approach ultimately aimed at trying to cure AIDS, scientists used genetic engineering in six patients to develop blood cells that are resistant to HIV, the virus that causes the disease.
It’s far too early to know if this scientific first will prove to be a cure, or even a new treatment. The research was only meant to show that, so far, it seems feasible and safe.
The concept was based on the astonishing case of an AIDS patient who seems to be cured after getting blood cells from a donor with natural immunity to HIV nearly four years ago in Berlin. Researchers are seeking a more practical way to achieve similar immunity using patients’ own blood cells.
The results announced Monday at a conference in Boston left experts cautiously excited.
"For the first time, people are beginning to think about a cure" as a real possibility, said Dr. John Zaia, head of the government panel that oversees gene therapy experiments. Even if the new approach doesn’t get rid of HIV completely, it may repair patients’ immune systems enough that they can control the virus and not need AIDS medicines — "what is called a functional cure," he said.
Carl Dieffenbach, AIDS chief at the National Institute of Allergy and infectious diseases, agreed.
"We’re hopeful that this is sufficient to give the level of immune reconstitution similar to what was seen with the patient from Germany," he said.
This is the first time researchers have permanently deleted a human gene and infused the altered cells back into patients. Other gene therapy attempts tried to add a gene or muffle the activity of one, and have not worked against HIV.
The virus can damage the immune system for years before people develop symptoms and are said to have AIDS — acquired immune deficiency syndrome. The virus targets special immune system soldiers called T-cells. It usually enters these cells through a protein receptor, or “docking station,” called CCR5.
Some people (about 1 percent of whites; fewer of minorities) lack both copies of the CCR5 gene and are naturally resistant to HIV. One such person donated blood stem cells in 2007 to an American man living in Berlin who had leukemia and HIV.
The cell transplant appears to have cured both problems, but finding such donors for everyone with HIV is impossible, and transplants are medically risky.
So scientists wondered: Could a patient’s own cells be used to knock out the CCR5 gene and create resistance to HIV?
A California biotechnology company, Sangamo (SANG-uh-moh) BioSciences Inc., makes a treatment that can cut DNA at precise locations and permanently “edit out” a gene.
Dr. Jacob Lalezari, director of Quest Clinical Research of San Francisco, led the first test of this with the company and colleagues at the University of California in San Francisco and Los Angeles.
He warned that it would be “way overstated” to suggest that the results so far are a possible cure.
"It’s an overreach of the data. There are a lot of people out there with hopes and dreams around the C-word," so caution is needed.
In the study, six men with HIV had their blood filtered to remove a small percentage of their T-cells. The gene-snipping compound was added in the lab, and about one-fourth of the cells were successfully modified. The cells were mixed with growth factors to make them multiply and then infused back into the patients.
Three men received about 2.5 billion modified cells. Three others received about 5 billion. Three months later, five men had three times the number of modified cells expected. As much as 6 percent of their total T-cells appear to be the new type — resistant to HIV, Lalezari said. The sixth man also had modified cells, but fewer than expected. In all six patients, the anti-HIV cells were thriving nearly a year after infusion, even in tissues that can hide HIV when it can’t be detected in blood. “The cells are engrafting — they’re staying in the bloodstream, they’re expanding over time,” said Lalezari, who has no personal financial ties to Sangamo, the study’s sponsor. The only side effect was two days of flulike symptoms. It will take longer to determine safety, but several AIDS experts said they were encouraged so far. “It is a huge step” and a first for the field of genetics, said John Rossi, a researcher at City of Hope in Duarte, Calif., where he and Zaia plan another study to test Sangamo’s approach. “The idea is if you take away cells the virus can infect, you can cure the disease.” On Wednesday, Dr. Carl June, a gene therapy expert at the University of Pennsylvania, will report partial results from a second, federally funded study of 10 people testing Sangamo’s product. He treated his first patient with it in July 2009. Many questions remain: • People born without the CCR5 gene are generally healthy, but will deleting it have unforeseen consequences? • Will HIV find another way into cells? Certain types of the virus can use a second protein receptor, though this is less common and usually when AIDS is advanced. Sangamo is testing a similar approach aimed at that protein, too. • How long will the modified cells last? Will more be needed every few years? • Could doctors just infuse Sangamo’s product rather than removing cells and modifying them in the lab? • What might this cost? Sangamo spokeswoman Liz Wolffe said it’s too early in testing to guess, but it would be “a premier-priced” therapy — in the neighborhood of Dendreon Corp.’s new prostate cancer immune therapy, Provenge — $93,000. Yet AIDS drugs can cost $25,000 a year, so this could still be cost-effective, especially if it’s a cure. Jay Johnson, 50, who works for Action AIDS, an advocacy and service organization in Philadelphia, had the treatment there in September. “My results are excellent,” he said. “The overall goal is to not have to take medication, and then hopefully lead maybe to a cure.” Matt Sharp, 54, of suburban San Francisco, also had the treatment in September. “I would trade anything to not have to take a handful of medications every day for the rest of my life and suffer all the consequences and side effects,” he said. “I may not live long enough to see the cure, but I always hoped for a chance.” ___ Online: AIDS information: http://www.aidsinfo.nih.gov andhttp://www3.niaid.nih.gov/topics/HIVAIDS/
Should you let yourself have that midnight snack if you’re having trouble sleeping and you think hunger might be part of the problem? Here are five foods that can actually help you drift off:
Can’t Get a Good Night’s Sleep? 5 Surprising Reasons
1. Cherries. Fresh and dried cherries are one of the only natural food sources of melatonin, the chemical that controls the body’s internal clock to regulate sleep. Researchers who tested tart cherries and found high levels of melatonin recommend eating them an hour before bedtime or before a trip when you want to sleep on the plane.
2. Bananas. Pottasium and magnesium are natural muscle relaxants, and bananas are a good source of both. They also contain the amino acid L-tryptophan, which gets converted to 5-HTP in the brain. The 5-HTP in turn is converted to serotonin (a relaxing neurotransmitter) and melatonin.
3. Toast. Carbohydrate-rich foods trigger insulin production, which induces sleep by speeding up the release of tryptophan and serotonin, two brain chemicals that relax you and send you to sleep..
4. Oatmeal. Like toast, a bowl of oatmeal triggers a rise in blood sugar, which in turn triggers insulin production and the release of sleep-inducing brain chemicals. Oats are also rich in melatonin, which many people take as a sleep aid..
5. Warm milk. Like bananas, milk contains the amino acid L-tryptophan, which turns to 5-HTP and releases relaxing serotonin. It’s also high in calcium, which promotes sleep.
By Amy S. D. Lee, MS, WHCRNP, Nurse Practitioner Feb 25, 2011
I sat in horror the other day as I read about the female reporter who was separated from her news crew in Egypt and brutally raped and beaten by an angry mob. And, I wondered in bewilderment, how the U.S. Congress could ever think that they could begin to “redefine” rape in order to control how federal money would be spent on services for rape victims. Recently, I listened intently as one of our hospital residents described the rape statistics that 1 in 8 women will be sexually assaulted in their lifetime. Unfortunately, only 1 in 6 will report the rape, and only 6 percent of the rapists will serve any time for their crime. When discussing those statistics with a friend, a former prosecuting attorney in the District Attorney’s office in Atlanta, she noted flatly that the cases are almost impossible to convict. And, I’ll always remember, so sadly, my college friend who was raped by her furniture deliveryman before he stabbed her to death. It’s a subject we all turn away from but it’s clearly one that needs to be discussed.
What is rape?
The legal definition of rape in most states is the forcible act of sexual relations against that person’s will. Lack of consent is a necessary element in every rape, although not a qualifier in the case of a minor or someone who is incapacitated. Most states consider rape legally “sexual assault” and will further break it down into degrees of assault. The rape may occur to a woman or a man but the overwhelming majority of cases happen to women. Incidence of rape increases in the settings of war. It is important to remember that rape is a violent act – not a sexual act. The sexual nature is simply a means to the violence.
What do you do if you are raped?
The highest incidence of rape occurs in younger women in their teens and early 20s but every woman is a susceptible victim. Women who are raped exhibit a wide range of emotional responses. The first thing most women want to do is clean up and scrub away the violation. This is the worst thing to do since it also scrubs away all of the evidence. If you are raped, go to the closest Emergency Room and bring yourself to tell someone there the truth. Don’t change clothes or shower or allow anyone to touch you. The police will come talk with you and special nurses or doctors (depending on where you are) will come and perform a complete exam for evidence. They will take your clothes, take samples, and take pictures. If you are not sure if you are able or willing to press charges, let them do the exam anyway.
By federal law, most states now have procedures in place to do the exam and store the evidence for you. You may find that several months later you may want to press charges. You should also then seek out a counselor. Most areas have rape hotlines and rape support groups. They can be valuable for your mental health. And overall, remember, you didn’t do anything to invite this. This was a violent assault on you and now you must become a survivor.
Hey. I don't know if this is a problem but every time I drink coffee (black or brown) with 2 tablespoons of brown sugar - my tummy aches, really bad and then after that I have to go to the bathroom. Am I allergic to it or it's just normal that I get rid of my waste after indulging myself in a cup of coffee? It's bothering me but my mum finds it normal.
Caffeine can cause indigestion because it stimulates excess production of stomach acid. Aside from being a stimulant, caffeine is also a diuretic, so it can cause you to urinate more often, and a laxative, which promotes movement of your colon and can cause loose bowel movements.
However, food allergies can also manifest in gastrointestinal disturbances like nausea, vomiting, diarrhea and abdominal cramping so I wouldn’t rule it out entirely.
But it’s more likely that your stomach disturbance is caused by the caffeine, so I recommend:
(1) switching to decaffeinated coffee (although some reports state that the effects are present in both caffeinated and decaffeinated coffee)
(2) add milk/cream to coffee to reduce the acidity (equals less tummy aches; granted that you’re not lactose intolerant)
(3) to NOT take coffee on an empty stomach (reduces absorption rate, decrease incidence of effects)
February is Heart Health month, and by now, you’ve read all about the heart-healthy benefits of good fats, whole grains, and stress reduction — but did you know that you can protect your heart by flossing your teeth or topping your toast with marmalade? Read on to find out more surprising ways to keep your heart pumping strong!
Take this advice to heart, but if you have heart issues, don’t stop taking your medications; always consult with your physician any time you begin a new health regime.
1. Floss Your Teeth, Save Your Heart
Your dentist has been telling you for years about the importance of flossing. It turns out that flossing not only protects your teeth and gums, but also potentially your heart. For a long time, observational studies have found that people with periodontal disease have significantly higher odds of developing cardiovascular disease. While experts are not sure exactly why taking care of your teeth is linked with better heart health, they speculate that bacteria from your mouth may stick to the fatty plaques in your bloodstream, directly contributing to blockages. Another theory is that these oral bacteria travel through your body, triggering inflammation that causes the blood cells to swell, then narrowing an artery. While more studies are needed to confirm the connection, it’s never a bad idea to floss once a day!
2. A Nap a Day Keeps Heart Disease Away
One of the best ways to lower stress on your heart is to take a nap during the middle of the day. Chinese medicine has long observed that, in the body’s circadian rhythms, noontime is the peak hour for the heart. Therefore, Chinese doctors advise calming activities and rest at this time of day to maintain the health of the cardiovascular system. Researchers have found that men who napped at least thirty minutes a day were 30 percent less likely to develop heart disease than those who didn’t nap. A siesta is a sign of wisdom, not laziness!
3. Pets: Heartwarming and Heart Protecting
Getting a pet is a great boon to heart health. A study reported in the Medical Journal of Australia found that, in general, pet owners have lower blood pressure, triglycerides, and cholesterol levels than people who do not own pets. Having a cat companion could cut your heart attack risk by nearly one third! According to a study by the Minnesota Stroke Institute, which followed over 4,000 cat owners during a 10-year period, being a feline owner can significantly decrease the chance of dying from heart disease. Another study, published in the American Journal of Cardiology, found that male dog owners were significantly less likely to die within one year after a heart attack than those who did not own a dog. Man’s best friend helps your heart in yet another way — all those daily walks add up to real cardiovascular benefits.
4. Peel Away Cholesterol with Orange Rind
Plaque in your arteries narrows the artery over time, impairing blood flow and dramatically increasing your risk for heart disease. Here’s a simple way to keep your arteries healthy: grate a little orange peel into your food regularly. In Chinese medicine, orange peel has been traditionally used to improve digestion of fatty and rich foods, and it is often found in traditional Chinese dishes with red meat. It turns out that orange peel may actually lower cholesterol better than some current medications, and without the side effects. Studies show that compounds called polymethosylated flavones (PMFs), found in pigments of orange and tangerines, reduce bad cholesterol (LDL) without altering the level of good cholesterol(HDL). Who would guess that orange-peel laden marmalade would also be good for lowering LDL cholesterol?
5. Celery: Just Juice It
High blood pressure is often the root cause of stroke, heart disease, and kidney failure. A time-tested Chinese remedy for this condition is fresh celery juice, which can be made with a blender or a juicer. Drinking one to two large glasses a day can help prevent high blood pressure or restore it to normal in those who already have high blood pressure. Studies have found that celery stalks are packed with more than a dozen anti-inflammatory agents, including apigenin, a cox2-inhibiting compound similar to some anti-inflammatory drugs.
6. Heart Health with Hawthorn Berries
Widely used since the seventeenth century by European herbalists, the hawthorn berry was traditionally considered a digestive aid for heavy meats and rich foods, as well as a potent activator of the circulatory system. Today it is used to cleanse the blood of plaque and other toxins. Recent European studies of this bioflavanoid-rich plant have confirmed its cardiovascular benefits, including lowering blood pressure during exertion, strengthening the heart muscle, and improving blood flow to the heart and throughout the body. Additionally, hawthorn has also been shown to lower cholesterol and balance blood sugar. You can make hawthorn berry tea or take it in supplement form. Available in powder, capsules, and liquid extracts, a typical dosage is up to 500 mg daily.
Bonus Tip: If you want to take your heart health one step further, you can try taking tonic herbs that support a robust and open cardiovascular system, such as Super Clarity.
You can find many more ways to protect your heart and live to 100 in Secrets of Longevity: Hundreds of Ways to Live to Be 100, which is now available on Kindle. If you are interested in a lifestyle program, designed to transform your health and lengthen your years, check out my new book Secrets of Longevity 8-Week Program.
I invite you to visit often and share your own personal health and longevity tips with me.
Air pollution triggers more heart attacks than using cocaine and poses as high a risk of sparking a heart attack as alcohol, coffee and physical exertion, scientists said on Thursday.
Sex, anger, marijuana use and chest or respiratory infections and can also trigger heart attacks to different extents, the researchers said, but air pollution, particularly in heavy traffic, is the major culprit.
The findings, published in The Lancet journal, suggest population-wide factors like polluted air should be taken more seriously when looking at heart risks, and should be put into context beside higher but relatively rarer risks like drug use.
Tim Nawrot of Hasselt University in Belgium, who led the study, said he hoped his findings would also encourage doctors to think more often about population level risks.
"Physicians are always looking at individual patients — and low risk factors might not look important at an individual level, but if they are prevalent in the population then they have a greater public health relevance," he said in a telephone interview.
The World Health Organization (WHO) describes air pollution as “a major environmental risk to health” and estimates that it causes around 2 million premature deaths worldwide every year.
Nawrot’s team combined data from 36 separate studies and calculated the relative risk posed by a series of heart attack triggers and their population-attributable fraction (PAF) — in other words the proportion of total heart attacks estimated to have been caused by each trigger.
The highest risk PAF was exposure to traffic, followed by physical exertion, alcohol, coffee, air pollution, and then things like anger, sex, cocaine use, smoking marijuana and respiratory infections.
"Of the triggers for heart attack studied, cocaine is the most likely to trigger an event in an individual, but traffic has the greatest population effect as more people are exposed to (it)," the researchers wrote. "PAFs give a measure of how much disease would be avoided if the risk was no longer present."
A report published late last year found that air pollution in many major cities in Asia exceeds the WHO’s air quality guidelines and that toxic cocktails of pollutants results in more than 530,000 premature deaths a year.
While passive smoking was not included in this study, Nawrot said the effects of second-hand smoke were likely to be similar to that of outdoor air pollution, and noted previous research which found that bans on smoking in public places have significantly reduced heart attack rates.
British researchers said last year that a ban on smoking in public places in England led to a swift and significant drop in the number of heart attacks, saving the health service 8.4 million pounds ($13 million) in the first year.
Tim Chico, a heart specialist at the University of Sheffield who was not involved in this research, said it would help health authorities focus on which are the most important triggers.
"However, what triggers the heart attack should be considered the "last straw." The foundations of heart disease that lead to a heart attack are laid down over many years," he said in an emailed comment. "If someone wants to avoid a heart attack they should focus on not smoking, exercising, eating a healthy diet and maintaining their ideal weight."
What is the difference between being overweight and being obese?
Overweight and obesity are both labels for ranges of weight that are greater than what is generally considered healthy for a given height. The terms also identify ranges of weight that have been shown to increase the likelihood of certain diseases and other health problems.
For adults, overweight and obesity ranges are determined by using weight and height to calculate a number called the “body mass index” (BMI).
An adult who has a BMI between 25 and 29.9 is considered overweight.
An adult who has a BMI of 30 or higher is considered obese.
See the following table for an example.
It is important to remember that although BMI correlates with the amount of body fat, BMI does not directly measure body fat. As a result, some people, such as athletes, may have a BMI that identifies them as overweight even though they do not have excess body fat.
For children and teens, BMI ranges above a normal weight have different labels (at risk of overweight and overweight). Additionally, BMI ranges for children and teens are defined so that they take into account normal differences in body fat between boys and girls and differences in body fat at various ages.
What are some of the factors that contribute to overweight and obesity?
Researchers have found that several factors can contribute to the likelihood of someone’s becoming overweight or obese.
Behaviors. What people eat and their level of physical activity help determine whether they will gain weight. A number of factors can influence diet and physical activity, including personal characteristics of the individual, the individual’s environment, cultural attitudes, and financial situation.
Genetics. Heredity plays a large role in determining how susceptible people are to becoming overweight or obese. Genes can influence how the body burns calories for energy and how the body stores fat.
How does being overweight or obese affect a person’s health?
When people are or overweight or obese, they are more likely to develop health problems such as the following:
Dyslipidemia (for example, high total cholesterol or high levels of triglycerides)
Type 2 diabetes
Coronary heart disease
Sleep apnea and respiratory problems
Some cancers (endometrial, breast, and colon)
The more overweight a person is, the more likely that person is to have health problems. Among people who are overweight and obese, weight loss can help reduce the chances of developing these health problems. Studies show that if a person is overweight or obese, reducing body weight by 5 percent to 10 percent can improve one’s health.
What are some suggestions for losing weight?
Most experts recommend that someone attempting to lose a large amount of weight consult with a personal physician or health care professional before beginning a weight-loss program.
Aim for a healthy weight. People who need to lose weight should do so gradually, at a rate of one-half to two pounds per week.
Be active. The safest and most effective way to lose weight is to reduce calories and increase physical activity.
How can physical activity help prevent overweight and obesity?
Physical activity, along with a healthy diet, plays an important role in the prevention of overweight and obesity. In order to maintain a stable weight, a person needs to expend the same amount of calories as he or she consumes.
Although the body burns calories for everyday functions such as breathing, digestion, and routine daily activities, many people consume more calories than they need for these functions each day. A good way to burn off extra calories and prevent weight gain is to engage in regular physical activity beyond routine activities.
If you eat 100 more food calories a day than you burn, you’ll gain about 1 pound in a month. That’s about 10 pounds in a year. The bottom line is that to lose weight, it’s important to reduce calories and increase physical activity.
A tourniquet test (also known as a Rumpel-Leede Capillary-Fragility Test or simply a capillary fragility test) determines capillary fragility. It is a clinical diagnostic method to determine a patient’s haemorrhagic tendency. It assesses fragility of capillary walls and is used to identify thrombocytopenia (a reduced platelet count).
The test is defined by the WHO as one of the necessary requisites for diagnosis of Dengue fever. A blood pressure cuff is applied and inflated to a point between the systolic and diastolic blood pressures for five minutes. The test is positive if there are 10 or more petechiae per square inch. In DHF the test usually gives a definite positive result with 20 petechiae or more.
This test does not have high specificity. Interfering factors with this test are women who are premenstrual, postmenstrual and not taking hormones, or those with sun damaged skin, since all will have increased capillary fragility.
By Amy S. D. Lee, MS, WHCRNP, Nurse Practitioner Feb 11, 2011
It seems like everything we read these days tells us that we must breastfeed our babies. Research indicates that breastfed babies have better immunity and perhaps even better intelligence! But I think that generalization is unfair to mothers who simply can’t breastfeed. It wasn’t that long ago that breastfeeding was simply unfashionable. Somehow that generation of bottle fed babies managed to survive. So let’s talk about the true realities of breastfeeding.
Healthy breast milk is good for a baby. We know that it departs early immunity to the baby and protects them from germs that their baby immune systems may have trouble fighting off. Formula companies have tried for years to simulate breast milk but have never succeeded in an exact replica. The fats and nutrition in breast milk are completely unique. Some breast-fed babies have demonstrated higher IQs later in life. The vision capability of babies is known to be just about the distance from the breast to their mother’s face. They know their mother’s face and smell. They bond closely during feeding.
So why wouldn’t you want to breastfeed? Unfortunately, some medical conditions and medications make the breast milk bad for the baby. HIV infected mothers can pass the disease to their babies through their breast milk. Certain medications can be passed to the baby through the breast milk that may be detrimental to the baby. What about babies that are adopted? Their adoptive mother isn’t prepared to breastfeed since the pregnancy hormones prepare the breast for breastfeeding. Some women have had breast surgery that prevents them from breast feeding. For others it simply doesn’t work out. I have one friend who developed horrible abscesses throughout her breasts. And some women just don’t feel comfortable breastfeeding.
So What Should You Do?
I recommend that if you are healthy and it is okay with your healthcare provider, try breastfeeding. It’s often a great experience for many women and babies. Even if you only do it for a few weeks, the baby gets the benefit of those early immunities. And you may even find that you’ll want do it for much longer!
If you can’t breastfeed, choose a good formula with the help of your pediatrician—and hold the baby close enough to see you and smell you during feedings. Most importantly, do not despair; there are plenty of bottle fed babies out there who have become healthy, productive and intelligent members of society! Life is about a lot more than how you were fed as a baby!
Use your cell phone only for short calls or texts, or use a hands-free device that keeps the phone—and the radio frequency energy it emits—away from your head. The point is more to preempt any risk than to protect against a proven danger: Evidence that cell phones increase brain cancer risk is “neither consistent nor conclusive,” says the President’s Cancer Panel report. But a number of review studies suggest there’s a link.
009) Prevent Cancer: Ask Your Doctor About Breast Density
Women whose mammograms have revealed breast density readings of 75% or more have a breast cancer risk 4 to 5 times higher than that of women with low density scores, according to recent research. One theory is that denser breasts result from higher levels of estrogen—making exercise particularly important (see #8). “Shrinking your body fat also changes growth factors, signaling proteins such as adipokines and hormones like insulin in ways that tend to turn off cancer-promoting processes in cells,” Walker says.
A solvent known as perc (short for perchloroethylene) that’s used in traditional dry cleaning may cause liver and kidney cancers and leukemia, according to an EPA finding backed in early 2010 by the National Academies of Science. The main dangers are to workers who handle chemicals or treated clothes using older machines, although experts have not concluded that consumers are also at increased cancer risk. Less toxic alternatives: Hand-wash clothes with mild soap and air-dry them, spot cleaning if necessary with white vinegar.
007) Prevent Cancer: Burn Off Your Breast Cancer Risk
Moderate exercise such as brisk walking 2 hours a week cuts risk of breast cancer 18%. Regular workouts may lower your risks by helping you burn fat, which otherwise produces its own estrogen, a known contributor to breast cancer.
They’re a stellar source of selenium, an antioxidant that lowers the risk of bladder cancer in women, according to research from Dartmouth Medical School. Other studies have found that people with high blood levels of selenium have lower rates of dying of lung cancer and colorectal cancer. Researchers think selenium not only protects cells from free radical damage but also may enhance immune function and suppress formation of blood vessels that nourish tumors.
i watched your video of using tomato as a natural way of refreshing face, i just wanna ask what's the purpose of refined sugar?? anyways, nice blog of yours. =) i enjoy reading your healthy tips as well as the beauty tips. =)
Hello,please enable your Tumblr Ask.
The refined sugar would help the tomato for exfoliation. So the sugar (organic) will be a natural scrub for the face as well.
005) Prevent Cancer: Load up on really green greens
Next time you’re choosing salad fixings, reach for the darkest varieties. The chlorophyll that gives them their color is loaded with magnesium, which some large studies have found lowers the risk of colon cancer in women. “Magnesium affects signaling in cells, and without the right amount, cells may do things like divide and replicate when they shouldn’t,” says Walker. Just 1/2 cup of cooked spinach provides 75 mg of magnesium, 20% of the daily value.
Drinking plenty of water and other liquids may reduce the risk of bladder cancer by diluting the concentration of cancer-causing agents in urine and helping to flush them through the bladder faster. Drink at least 8 cups of liquid a day, suggests the American Cancer Society.
Java lovers who drank 5 or more cups of caffeinated coffee a day had a 40% decreased risk of brain cancer, compared with people who drank the least, in a 2010 British study. A 5-cup-a-day coffee habit reduces risks of oral and throat cancer almost as much. Researchers credit the caffeine: Decaf had no comparable effect. But coffee was a more potent protector against these cancers than tea, which the British researchers said also offered protection against brain cancer.
002) Prevent Cancer: Marinate Meat before Grilling
Processed, charred, and well-done meats can contain cancer-causing heterocyclic amines, which form when meat is seared at high temperatures, and polycyclic aromatic hydrocarbons, which get into food when it’s charcoal broiled. “The recommendation to cut down on grilled meat has really solid scientific evidence behind it,” says Cheryl Lyn Walker, PhD, a Professor of carcinogenesis at the University of Texas M.D. Anderson Cancer Center. If you do grill, add rosemary and thyme to your favorite marinade and soak meat for at least an hour before cooking. The antioxidant-rich spices can cut HCAs by as much as 87%, according to research at Kansas State University.
You’ll reduce your exposure to known or suspected carcinogens and hormone-disrupting chemicals. A new report from the President’s Cancer Panel on how to reduce exposure to carcinogens suggests that home-filtered tap water is a safer bet than bottled water, whose quality often is not higher—and in some cases is worse—than that of municipal sources, according to a study by the Environmental Working Group. (Consumer Reports’ top picks for faucet-mounted filters: Culligan, Pur Vertical, and the Brita OPFF-100.) Store water in stainless steel or glass to avoid chemical contaminants such as BPA that can leach from plastic bottles.
I'm 17 & 5'3 and 170 lbs though. I haven't gained weight for 5 months. It's hard for me to lose weight! What can I do? :(
" I haven’t gained weight for 5 months. It’s hard for me to lose weight!" — So did you mean, there’s no changes in your weight for 5 months? now your problem is, how are you going to lose weight?
So what I can advice is to eat small frequent meals. A high calorie intake with no exercise is not good. You should at least cut down your calorie intake. You can have your exercise (I prefer cardio workout - a treadmill will do or just have jogging for at least 1 mile.) or have at least 20-30 minutes of exercise.
Drink lots of water to eliminate the toxins from your body.
Have a discipline. If you want to lose weight, do it. :)
you said things about the prevention of having blackheads, but how you remove those when it is already in your face? thank you ms nurse. love you:)
I saw this on a site. I just have to copy it since it’s right.
HOW TO REMOVE BLACKHEADS - 3 SIMPLE STEPS
There is an efficient way to remove blackheads without making the condition worse. Follow these 3 steps and you should be well on your way to better looking skin.
1. Wash Your Face
The first thing you need to do is to wash your face with a facial cleanser, preferably one that contains benzoyl peroxide as an ingredient. Benzoyl peroxide works to exfoliate the skin so that dirt and dead skin cells are washed away. Massage the cleanser onto your face with your fingers for several minutes. Remember not to forcefully scrub your face as this will irritate the skin.
Rinse your face thoroughly and dry it with a towel using a gentle, patting motion. After this, you will need to steam your face as this helps soften the blackheads and will later make for easier extraction of the bump. If you do not have a facial steamer, you can use warm water to rinse your face.
2. Clear Your Blackheads
The most common technique for taking out blackheads is to use a blackhead remover. This is usually a metal stick with a hole at the end. When using equipment to extract blackheads, make sure they are thoroughly cleansed and sterilized.
Position the hole over the blackhead and exert mild pressure until you see the blackhead come out. Take utmost care in using the extractor as too much pressure can lead to scarring. Once you have taken out the blackheads, put on an antibacterial ointment to keep the area from getting infected.
If you are not too keen on using an extractor, you can also apply a mask on your face. Leave it on for 10 to 15 minutes before washing it off with warm water.
For a quick fix, you can also use pores strips which are sheets of paper with some sort of mixture at the bottom that helps peel off blackheads from your face. Some types of pore strips can be placed directly on the nose, others require you to wet the strip to activate the mixture and make it stick to your nose. Peel off the strip after 10 minutes. This is a convenient way to get rid of blackheads although take note that this solution is temporary.
3. Cleanse Your Face Regularly
In order to prevent the blackheads from recurring, make it a habit to regularly cleanse your face. A good skin care regimen involves the use of a facial wash, toner and moisturizer.
I searched the ways for you. :) And I love you too anon.
Somnambulism, also known as sleepwalking, is thought to affect between 1% and 15% of the American population. The causes are cited to be anything from restless leg syndrome to mental illness, and the manifestations are even wider spread. There are some cases where people have been said to cook, eat, engage in sexual activity, and even murder…all in their sleep.
When we sleep, that sleep undergoes several stages. You have your NREM sleep, which is divided into stage 1, stage 2, and stage 3 and 4. Stage 1 is that light sleep, while stage 2 is a consolidated sleep period, stages 3 and 4 are deep sleep stages (known as “slow-wave sleep”), and after these stages we reach REM state. REM sleep (REM stands for Rapid Eye Movement) is where your eyes move rapidly under your eyelids, your respiration and heart rate can be irregular, and this is when you’re most likely to dream. Despite the rapid movement of the eyes, the respiration and heart rate irregularities, and the fact that your brain is possibly occupied by a dream, this is supposed to be our most restful stage of sleep, and it accounts for 90-120 minutes of a total night’s sleep. “Normal” sleepwalking occurs during the REM state, and if you do it you are considered to have a “REM State Sleeping Disorder.”
Sleepwalking can occur outside of the REM state, during stages 3 and 4 of NREM, during that deepest sleep. Specialists aren’t completely sure what causes the high-voltage delta waves that characterize sleepwalking. Some think it is a reactionary condition brought on by exhaustion, fever, or something similar. In some cases it is. In other cases, somnambulism occurs because of much deeper seated problem. For instance, many drug users are known to sleepwalk, and people with schizophrenia and anxiety disorders are more likely to be sleepwalkers. New research shows that sufferers of Tourette Syndrome and frequent migraine headaches are more prone to sleepwalk.
So, what of these people who claim to have had sex, cooked, sent email, and even murdered in their sleep. This is because, as we mentioned before, REM stage sleepwalking is one thing, but NREM sleepwalking is something else. During that stage 3 and 4 sleep, the brain is supposed to be, for lack of a better term, quiet. In a NREM state sleeping disorder, part of the brain wakes up, and causes the person to do all sorts of things. If that person is predisposed or in the “right” mindframe, they certainly can be capable of murder.
And, given that certain types of insomnia are considered a mental illness, they’ll probably get away with it.
The most important thing to do is to wash your face for at least twice a day. (Early morning ang before going to sleep). During summer, wash it more often to prevent oily skin. Use warm water to open the pores, allowing deep penetration of skin by the soap you are using. (Use mild soap in your face) But when you’re going to rinse, use cold water to close the pores.
Drink at least 6 to 8 glasses of water everyday. Water is the best way of removing toxins in the body.
Don’t eat too much fatty/oily food. It can cause acne.
Forget chicken noodle soup, orange juice, and other immunity-boosting foods, there may be a new way to relieve the common cold. A new review from the Cochran Collaboration found that taking zinc within 24 hours of coming down with the sniffles could decrease the duration and severity of a cold in healthy people.
While it’s not completely clear how zinc stops a cold, the studies concluded that upping your zinc intake cuts days off your sneezing, congestion, and coughing.
Many of the studies used zinc supplements, but there was no recommendation for how much or how long you should take zinc. If you feel the onset of a cold, adding a few zinc-rich foods into you diet may help.
Oysters contain the most zinc of any food—with 500% of your daily dose—but most people won’t be slurping those down on a regular basis. Instead turn to foods like pork tenderloin, chicken legs, baked beans, cashews, or even fortified cereals to start boosting your intake.
We love these delicious recipes that will make it easy to keep colds at bay:
The occasional manic Monday is a fact of modern life.
But if you’re under chronic stress—suffering a daily assault of stress hormones from a demanding job or a personal life in turmoil—symptoms may be subtler, says Stevan E. Hobfoll, PhD, chair of the department of behavioral sciences at Rush University Medical Center. If you experience any of the signs that follow, take some time out every day, he says, whether it’s to go for a walk or simply turn off your phone.
1. Weekend headaches
A sudden drop in stress can prompt migraines, says Todd Schwedt, MD, director of the Washington University Headache Center. Stick closely to your weekday sleeping and eating schedule to minimize other triggers.
2. Awful period cramps
The most stressed-out women are more than twice as likely to experience painful cramps as those who are less tense, a Harvard study found. Researchers blame a stress-induced imbalance of hormones. Hitting the gym can soothe cramps and stress, research shows, by decreasing sympathetic nervous system activity.
3. An achy mouth
A sore jaw can be a sign of teeth grinding, which usually occurs during sleep and can be worsened by stress, says Matthew Messina, DDS, a consumer advisor to the American Dental Association. Ask your dentist about a nighttime mouth guard—up to 70% of people who use one reduce or stop grinding altogether.
4. Odd dreams
Dreams usually get progressively more positive as you sleep, so you wake up in a better mood than you were in when you went to bed, says Rosalind Cartwright, PhD, an emeritus professor of psychology at Rush University Medical Center. But when you’re stressed, you wake up more often, disrupting this process and allowing unpleasant imagery to recur all night. Good sleep habits can help prevent this; aim for 7 to 8 hours a night, and avoid caffeine and alcohol close to bedtime.
5. Bleeding gums
According to a Brazilian analysis of 14 past studies, stressed-out people have a higher risk of periodontal disease. Chronically elevated levels of the stress hormone cortisol may impair the immune system and allow bacteria to invade the gums, say researchers. If you’re working long hours and eating dinner at your desk, keep a toothbrush on hand. And “protect your mouth by exercising and sleeping more, which will help lower stress,” says Preston Miller, DDS, past president of the American Academy of Periodontology.
6. Out-of-nowhere acne
Stress increases the inflammation that leads to breakouts, says Gil Yosipovitch, MD, a clinical professor of dermatology at Wake Forest University. Smooth your skin with a lotion containing skin sloughing salicylic acid or bacteria-busting benzoyl peroxide, plus a noncomedogenic moisturizer so skin won’t get too dry. If your skin doesn’t respond to treatment within a few weeks, see your doctor for more potent meds.
7. A sweet tooth
Don’t automatically blame your chocolate cravings on your lady hormones—stress is a more likely trigger. When University of Pennsylvania researchers surveyed pre- and postmenopausal women, they found only a small decrease in the prevalence of chocolate cravings after menopause—smaller than could be explained by just a hormonal link. Study authors say it’s likely stress, or other factors that can trigger women’s hankering for chocolate.
8. Itchy skin
A recent Japanese study of more than 2,000 people found that those with chronic itch (known as pruritis) were twice as likely to be stressed out as those without the condition. Although an annoying itch problem can certainly cause stress, experts say it’s likely that feeling anxious or tense also aggravates underlying conditions like dermatitis, eczema, and psoriasis. “The stress response activates nerve fibers, causing an itchy sensation,” explains Yosipovitch.
9. Worse-than-usual allergies
In a 2008 experiment, researchers from Ohio State University College of Medicine found that allergy sufferers had more symptoms after they took an anxiety-inducing test, compared with when they performed a task that did not make them tense. Stress hormones may stimulate the production of IgE, a blood protein that causes allergic reactions, says study author Janice Kiecolt-Glaser, PhD.
Anxiety and stress can cause stomachaches, along with headaches, backaches, and insomnia. One study of 1,953 men and women found that those experiencing the highest levels of stress were more than three times as likely to have abdominal pain as their more-relaxed counterparts.
The exact connection is still unclear, but one theory holds that the intestines and the brain share nerve pathways; when the mind reacts to stress, the intestines pick up the same signal. Because of this link, learning to manage stress with the help of a clinical psychologist, meditation, or even exercise can usually help relieve tummy trouble too. However, if you have frequent bellyaches, see your doc to rule out food allergies, lactose intolerance, irritable bowel syndrome, or an ulcer.